The world’s first placebo controlled clinical trial confirms the successful application of the kINPen® MED plasma jet in the treatment of diabetic foot ulcera: Reactivation and acceleration of wound healing scientifically confirmed
The Study
Population 65 diabetic foot wounds
Adult patients with diabetic foot syndrome
Wagner-Armstrong Classification grade 1 B and 2 B
Average age: 68.5 years (standard deviation 9.1 years)
Study centres
Two German hospitals:
HDZ NRW, University Hospital for the treatment of cardiac, vascular and diabetic diseases of the Ruhr University of Bochum, Bad Oeynhausen, Germany
Medical centre for cardiac and diabetic diseases, Karlsburg, Germany)
Methodology 62 wounds were randomised
31 wounds treated with standard wound therapy plus cold atmospheric plasma (CAP): 8 CAP applications (30s/cm² wound surface) within 14 days
31 wounds treated with standard wound therapy plus placebo control: 8 applications of placebo (simulated plasma) within 14 days
Primary study endpoints Reduction of wound surface, the infection status of the wound and microbial load compared to the start of the therapy
Results
Reduction of wound surface After 8 treatments, the CAP therapy achieved the following results when compared to the placebo (measured at visit No. 9):
Significant increase of wound healing
Reduction of overall wound surface
Faster relevant reduction of wound surface
Effect of cold plasma on activation of wound healing
CAP superior to placebo with regard to infection status and microbial load reduction
The results confirm that atmospheric cold plasma has its own inherent activating effect on wound healing
Privacy Policy
We are using cookies. Some of them are essential, while others help us to improve this website and your experience.
You can find more information in our "privacy policy". acceptprivacy policy
Manage consent
Privacy Overview
This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience.
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.